What it looks like:
Sudden swelling in one leg (usually calf)
Pain that feels like a deep cramp or “Charley horse”
Warmth, redness, or tenderness along a vein
Why it matters:
Pancreatic tumors can trigger a hypercoagulable state—making blood more likely to clot. This happens because cancer cells release substances that activate clotting factors.
🩺 Key fact: An unprovoked DVT (no surgery, injury, or long flight) in someone over 50 may be the first sign of hidden cancer—including pancreatic. In some cases, clots appear months before other symptoms.
Action: Seek medical evaluation immediately. A Doppler ultrasound can confirm DVT—and prompt further screening if needed.
🦵 2. Persistent, Radiating Leg or Thigh Pain
What it feels like:
