🦵 2. Persistent, Radiating Leg or Thigh Pain
What it feels like:
Deep, dull ache in the upper thighs or back of legs
Pain not linked to exercise or injury
Discomfort that worsens at night or with lying down
No relief from stretching or rest
Why it matters:
The pancreas sits near major nerve bundles (like the celiac plexus). As a tumor grows, it can irritate these nerves, causing referred pain—felt in areas the nerves serve, including the legs.
🔍 This is not typical muscle soreness. It’s progressive, constant, and unexplained.
Action: If leg pain persists >2 weeks with no clear cause—and especially if paired with fatigue, appetite loss, or back pain—mention it to your doctor.
🩹 3. Strange Rash on Shins: Necrolytic Migratory Erythema (NME)
What it looks like:
Red, blistering, scaly rash on shins, groin, or feet
Lesions that heal in one spot and reappear elsewhere
Skin that cracks, bleeds, or looks infected—but doesn’t respond to creams
Why it matters: